Interestingly, the manufacturers of statin drugs are fully aware of their ability to interfere with memory and learning and to cause “brain fog.” In fact, these side effects are listed on the insert of every statin prescription bottle. They filled in health questionnaires, were weighed and measured, and took a series of tests to assess their overall cognition and memory. The Mail Online, the Daily Telegraph and The Sun all included comments that statins may offer protection against memory loss. It stated that previous trials of such medication had not looked at memory or cognition specifically and so praised the new study as "good news" for those with concerns. "Statins do NOT cause memory loss despite fears they could harm cognitive health," reports the Mail Online. Samaras K, Makkar SR, Crawford JD, et al. The study found no link between the drugs and mental decline. The sign… They were followed up for 6 years, with 12 tests of their cognition and memory repeated every 2 years, so that people who took all the tests took them 4 times in total. So researchers adjusted the results to take account of a range of potential confounding factors including: They looked to see whether, after taking these factors into account, people who had never taken statins had more or less decline in cognition and memory over 6 years, compared to people who: All the people in the study showed some decline in memory and cognition over 6 years, regardless of whether they took statins or not. It comes following a new study by researchers in Australia which suggested that the cholesterol-lowering drugs should not be associated with a decline in memory or cognition. The researchers prepared for the results to be affected by the fact those taking statins are likely to have heart disease and high blood pressure. The reasons for this link are explained by Be Brain Fit: This study tested the memory and overall cognitive function of 1,037 people aged 70 to 90 at several points over a 6-year period. This includes eating a healthier diet and limiting alcohol consumption, with statins likely to be recommended should these measures not help. Statins are one of the most commonly prescribed drugs for high cholesterol in the United States. There is limited evidence to prove a cause-effect relationship, but talk to your doctor if you experience memory loss or confusion while taking statins. This study seems to suggest that fears over a link between statins and cognitive decline or memory loss are unfounded. 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However, the research is good news for people who are considering taking statins but are worried about possible side effects. Analysing the main measures of the tests, researchers found no difference between people who: There was also no difference between these groups in brain volume, as measured by the MRI scan. Statins do not harm the memory – and may prevent cognitive decline for some, Fears that statins can cause mental decline are unfounded, says study, The Times online (subscription online), 19 November 2019, STATINS 'OK FOR OAPS WITH ALZ' Statins do NOT cause memory loss and may even protect OAPs against Alzheimer’s, study finds, Statins do NOT cause memory loss despite fears they could harm cognitive health, major new study suggests. This meant that people who participated in all the tests would have taken them four times in total. Statins are widely used drugs in the UK. The type of study also means we are limited in how we can interpret the results. That could mean people prescribed statins have less memory loss – but not because of the statin. This study seems to suggest that fears over a link between statins and cognitive decline or memory loss are unfounded. Around half (529) had MRI scans to measure their brain volume, and 408 of them had the scan repeated after 4 years. Following the study, its researchers concluded that those with concerns about the risks of being prescribed the widely used medication should now feel "reassured" by the findings. Complete data was only available for 55% of the people who started the study, and those who dropped out were older and had lower cognitive scores. The NHS acknowledged that, while statins are "widely used drugs" in the UK, there have been some concerns raised over possible side effects. Find out more about statins and why they are used. explains more about how we use your data, and your rights. People who took any kind of cholesterol drug—a statin or some other type—were nearly four times more likely to report memory loss right after starting on the drug, compared with people who didn't take any kind of cholesterol drug. The study was funded by the Australian Government's National Health and Medical Research Council and published in the peer-reviewed Journal of the American College of Cardiology. People at higher risk for memory loss include those who are taking higher dosages, with metabolic syndromes, and who are taking lipophilic statins (these are statins that cross into the brain more easily than other … That means it’s hard to understand from the Mail Online story how the researchers carried out the study. Does this mean all cholesterol drugs, not just statins, affect memory?
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